The International Classification of Diseases (ICD) is an authoritative medical classification system of different diseases and conditions for clinical and management purposes. ICD indexing aims to assign a subset of ICD codes to a medical record. Since human coding is labour-intensive and error-prone, many studies employ machine learning techniques to automate the coding process. ICD coding is a challenging task, as it needs to assign multiple codes to each medical document from an extremely large hierarchically organized collection. In this paper, we propose a novel approach for ICD indexing that adopts three ideas: (1) we use a multi-level deep dilated residual convolution encoder to aggregate the information from the clinical notes and learn document representations across different lengths of the texts; (2) we formalize the task of ICD classification with auxiliary knowledge of the medical records, which incorporates not only the clinical texts but also different clinical code terminologies and drug prescriptions for better inferring the ICD codes; and (3) we introduce a graph convolutional network to leverage the co-occurrence patterns among ICD codes, aiming to enhance the quality of label representations. Experimental results show the proposed method achieves state-of-the-art performance on a number of measures.
Scientific paper summarization has been the focus of much recent research. Unlike previous research which summarizes only the paper in question, or which summarizes the paper and the papers that it references, or which summarizes the paper and the citing sentences from the papers that cite it, this work puts all three of these summarization techniques together. To accomplish this, we have, by utilizing the citation network, introduced a corpus for scientific document summarization that provides information about the document being summarized, the papers referenced by it, as well as the papers that have cited it. The proposed summarizer model utilizes the referenced articles as background information and citing articles to capture the impact of the scientific document on the research community. Another aspect of the proposed model is its ability to generate both the extractive and abstractive summaries in parallel. The parallel training helps the counterparts to improve their individual performance. Results have shown that the summaries are of high quality when considering the standard metrics.
Summarization of scientific articles often overlooks insights from citing papers, focusing solely on the document’s content. To incorporate citation contexts, we develop a model to summarize a scientific document using the information in the source and citing documents. It concurrently generates abstractive and extractive summaries, each enhancing the other. The extractive summarizer utilizes a blend of heterogeneous graph-based neural networks and graph attention networks, while the abstractive summarizer employs an autoregressive decoder. These modules exchange control signals through the loss function, ensuring the creation of high-quality summaries in both styles.
Understanding biological mechanisms requires determining mutual protein-protein interactions (PPI). Obtaining drug-drug interactions (DDI) from scientific articles provides important information about drugs. Extracting such medical entity interactions from biomedical articles is challenging due to complex sentence structures. To address this issue, our proposed model utilizes tree-transformers to generate the sentence representation first, and then a sentence-to-word update step to fine-tune the word embeddings which are again used by the tree-transformers to generate enriched sentence representations. Using the tree-transformers helps the model preserve syntactical information and provide semantic information. The fine-tuning provided by the continuous update step adds improved semantics to the representation of each sentence. Our model outperforms other prominent models with a significant performance boost on the five standard PPI corpora and a performance boost on the one benchmark DDI corpus that are used in our experiments.
Medical Subject Heading (MeSH) indexing refers to the problem of assigning a given biomedical document with the most relevant labels from an extremely large set of MeSH terms. Currently, the vast number of biomedical articles in the PubMed database are manually annotated by human curators, which is time consuming and costly; therefore, a computational system that can assist the indexing is highly valuable. When developing supervised MeSH indexing systems, the availability of a large-scale annotated text corpus is desirable. A publicly available, large corpus that permits robust evaluation and comparison of various systems is important to the research community. We release a large scale annotated MeSH indexing corpus, MeSHup, which contains 1,342,667 full text articles, together with the associated MeSH labels and metadata, authors and publication venues that are collected from the MEDLINE database. We train an end-to-end model that combines features from documents and their associated labels on our corpus and report the new baseline.
Citations are frequently used in publications to support the presented results and to demonstrate the previous discoveries while also assisting the reader in following the chronological progression of information through publications. In scientific publications, a citation refers to the referenced document, but it makes no mention of the exact span of text that is being referred to. Connecting the citation to this span of text is called citation linkage. In this paper, to find these citation linkages in biomedical research publications using deep learning, we provide a synthetic silver standard corpus as well as the method to build this corpus. The motivation for building this corpus is to provide a training set for deep learning models that will locate the text spans in a reference article, given a citing statement, based on semantic similarity. This corpus is composed of sentence pairs, where one sentence in each pair is the citing statement and the other one is a candidate cited statement from the referenced paper. The corpus is annotated using an unsupervised sentence embedding method. The effectiveness of this silver standard corpus for training citation linkage models is validated against a human-annotated gold standard corpus.
Due to the success of pre-trained language models, versions of languages other than English have been released in recent years. This fact implies the need for resources to evaluate these models. In the case of Spanish, there are few ways to systematically assess the models’ quality. In this paper, we narrow the gap by building two evaluation benchmarks. Inspired by previous work (Conneau and Kiela, 2018; Chen et al., 2019), we introduce Spanish SentEval and Spanish DiscoEval, aiming to assess the capabilities of stand-alone and discourse-aware sentence representations, respectively. Our benchmarks include considerable pre-existing and newly constructed datasets that address different tasks from various domains. In addition, we evaluate and analyze the most recent pre-trained Spanish language models to exhibit their capabilities and limitations. As an example, we discover that for the case of discourse evaluation tasks, mBERT, a language model trained on multiple languages, usually provides a richer latent representation than models trained only with documents in Spanish. We hope our contribution will motivate a fairer, more comparable, and less cumbersome way to evaluate future Spanish language models.
We develop a novel unified representation for the argumentation mining task facilitating the extracting from text and the labelling of the non-argumentative units and argumentation components—premises, claims, and major claims—and the argumentative relations—premise to claim or premise in a support or attack relation, and claim to major-claim in a for or against relation—in an end-to-end machine learning pipeline. This tightly integrated representation combines the component and relation identification sub-problems and enables a unitary solution for detecting argumentation structures. This new representation together with a new deep learning architecture composed of a mixed embedding method, a multi-head attention layer, two biLSTM layers, and a final linear layer obtain state-of-the-art accuracy on the Persuasive Essays dataset. Also, we have introduced a decoupled solution to identify the entities and relations first, and on top of that, a second model is used to detect distance between the detected related components. An augmentation of the corpus (paragraph version) by including copies of major claims has further increased the performance.
This paper presents a method for semi-automatically building a corpus of full-text English-language biomedical articles annotated with part-of-speech tags. The outcomes are a semi-automatic procedure to create a large silver standard corpus of 5 million sentences drawn from a large corpus of full-text biomedical articles annotated for part-of-speech, and a robust, easy-to-use software tool that assists the investigation of differences in two tagged datasets. The method to build the corpus uses two part-of-speech taggers designed to tag biomedical abstracts followed by a human dispute settlement when the two taggers differ on the tagging of a token. The dispute resolution aspect is facilitated by the software tool which organizes and presents the disputed tags. The corpus and all of the software that has been implemented for this study are made publicly available.
Research papers reflect scientific advances. Citations are widely used in research publications to support the new findings and show their benefits, while also regulating the information flow to make the contents clearer for the audience. A citation in a research article refers to the information’s source, but not the specific text span from that source article. In biomedical research articles, this task is challenging as the same chemical or biological component can be represented in multiple ways in different papers from various domains. This paper suggests a mechanism for linking citing sentences in a publication with cited sentences in referenced sources. The framework presented here pairs the citing sentence with all of the sentences in the reference text, and then tries to retrieve the semantically equivalent pairs. These semantically related sentences from the reference paper are chosen as the cited statements. This effort involves designing a citation linkage framework utilizing sequential and tree-structured siamese deep learning models. This paper also provides a method to create a synthetic corpus for such a task.
Currently, Medical Subject Headings (MeSH) are manually assigned to every biomedical article published and subsequently recorded in the PubMed database to facilitate retrieving relevant information. With the rapid growth of the PubMed database, large-scale biomedical document indexing becomes increasingly important. MeSH indexing is a challenging task for machine learning, as it needs to assign multiple labels to each article from an extremely large hierachically organized collection. To address this challenge, we propose KenMeSH, an end-to-end model that combines new text features and a dynamic knowledge-enhanced mask attention that integrates document features with MeSH label hierarchy and journal correlation features to index MeSH terms. Experimental results show the proposed method achieves state-of-the-art performance on a number of measures.
In the field of Natural Language Processing (NLP), extracting method entities from biomedical text has been a challenging task. Scientific research papers commonly consist of complex keywords and domain-specific terminologies, and new terminologies are continuously appearing. In this research, we find method terminologies in biomedical text using both rule-based and machine learning techniques. We first use linguistic features to extract method sentence candidates from a large corpus of biomedical text. Then, we construct a silver standard biomedical corpus composed of these sentences. With a rule-based method that makes use of the Stanza dependency parsing module, we label the method entities in these sentences. Using this silver standard corpus we train two machine learning algorithms to automatically extract method entities from biomedical text. Our results show that it is possible to develop machine learning models that can automatically extract method entities to a reasonable accuracy without the need for a gold standard dataset.
Hedging is a commonly used strategy in conversational management to show the speaker’s lack of commitment to what they communicate, which may signal problems between the speakers. Our project is interested in examining the presence of hedging words and phrases in identifying the tension between an interviewer and interviewee during a survivor interview. While there have been studies on hedging detection in the natural language processing literature, all existing work has focused on structured texts and formal communications. Our project thus investigated a corpus of eight unstructured conversational interviews about the Rwanda Genocide and identified hedging patterns in the interviewees’ responses. Our work produced three manually constructed lists of hedge words, booster words, and hedging phrases. Leveraging these lexicons, we developed a rule-based algorithm that detects sentence-level hedges in informal conversations such as survivor interviews. Our work also produced a dataset of 3000 sentences having the categories Hedge and Non-hedge annotated by three researchers. With experiments on this annotated dataset, we verify the efficacy of our proposed algorithm. Our work contributes to the further development of tools that identify hedges from informal conversations and discussions.
In natural language processing, the performance of a semantic similarity task relies heavily on the availability of a large corpus. Various monolingual corpora are available (mainly English); but multilingual resources are very limited. In this work, we describe a semi-automated framework to create a multilingual corpus which can be used for the multilingual semantic similarity task. The similar sentence pairs are obtained by crawling bilingual websites, whereas the dissimilar sentence pairs are selected by applying topic modeling and an Open-AI GPT model on the similar sentence pairs. We focus on websites in the government, insurance, and banking domains to collect English-French and English-Spanish sentence pairs; however, this corpus creation approach can be applied to any other industry vertical provided that a bilingual website exists. We also show experimental results for multilingual semantic similarity to verify the quality of the corpus and demonstrate its usage.
Argumentation in an experimental life science paper consists of a main claim being supported with reasoned argumentative steps based on the data garnered from the experiments that were carried out. In this paper we report on an investigation of the large scale argumentation structure found when examining five biochemistry journal publications. One outcome of this investigation of biochemistry articles suggests that argumentation schemes originally designed for genetic research articles may transfer to experimental biomedical literature in general. Our use of these argumentation schemes shows that claims depend not only on experimental data but also on other claims. The tendency for claims to use other claims as their supporting evidence in addition to the experimental data led to two novel models that have provided a better understanding of the large scale argumentation structure of a complete biochemistry paper. First, the claim graph displays the claims within a paper, their interactions, and their evidence. Second, another aspect of this argumentation network is further illustrated by the Model of Informational Hierarchy (MIH) which visualizes at a meta-level the flow of reasoning provided by the authors of the paper and also connects the main claim to the paper’s title. Together, these models, which have been produced by a manual examination of the biochemistry articles, would be likely candidates for a computational method that analyzes the large scale argumentation structure.
In recent NLP research, a topic of interest is universal sentence encoding, sentence representations that can be used in any supervised task. At the word sequence level, fully attention-based models suffer from two problems: a quadratic increase in memory consumption with respect to the sentence length and an inability to capture and use syntactic information. Recursive neural nets can extract very good syntactic information by traversing a tree structure. To this end, we propose Tree Transformer, a model that captures phrase level syntax for constituency trees as well as word-level dependencies for dependency trees by doing recursive traversal only with attention. Evaluation of this model on four tasks gets noteworthy results compared to the standard transformer and LSTM-based models as well as tree-structured LSTMs. Ablation studies to find whether positional information is inherently encoded in the trees and which type of attention is suitable for doing the recursive traversal are provided.
The advent of micro-blogging sites has paved the way for researchers to collect and analyze huge volumes of data in recent years. Twitter, being one of the leading social networking sites worldwide, provides a great opportunity to its users for expressing their states of mind via short messages which are called tweets. The urgency of identifying emotions and sentiments conveyed through tweets has led to several research works. It provides a great way to understand human psychology and impose a challenge to researchers to analyze their content easily. In this paper, we propose a novel use of a multi-channel convolutional neural architecture which can effectively use different emotion and sentiment indicators such as hashtags, emoticons and emojis that are present in the tweets and improve the performance of emotion and sentiment identification. We also investigate the incorporation of different lexical features in the neural network model and its effect on the emotion and sentiment identification task. We analyze our model on some standard datasets and compare its effectiveness with existing techniques.
This paper focuses on the real world application of scientific writing and on determining rhetorical moves, an important step in establishing the argument structure of biomedical articles. Using the observation that the structure of scholarly writing in laboratory-based experimental sciences closely follows laboratory procedures, we examine most closely the Methods section of the texts and adopt an approach of identifying rhetorical moves that are procedure-oriented. We also propose a verb-centric frame semantics with an effective set of semantic roles in order to support the analysis. These components are designed to support a computational model that extends a promising proposal of appropriate rhetorical moves for this domain, but one which is merely descriptive. Our work also contributes to the understanding of argument-related annotation schemes. In particular, we conduct a detailed study with human annotators to confirm that our selection of semantic roles is effective in determining the underlying rhetorical structure of existing biomedical articles in an extensive dataset. The annotated dataset that we produce provides the important knowledge needed for our ultimate goal of analyzing biochemistry articles.
The goal of text classification is to automatically assign categories to documents. Deep learning automatically learns effective features from data instead of adopting human-designed features. In this paper, we focus specifically on biomedical document classification using a deep learning approach. We present a novel multichannel TextCNN model for MeSH term indexing. Beyond the normal use of the text from the abstract and title for model training, we also consider figure and table captions, as well as paragraphs associated with the figures and tables. We demonstrate that these latter text sources are important feature sources for our method. A new dataset consisting of these text segments curated from 257,590 full text articles together with the articles’ MEDLINE/PubMed MeSH terms is publicly available.